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Capillary Electrophoresis - Mass Spectrometry (CE-MS) - Principles and Applications (Hardcover)
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Capillary Electrophoresis - Mass Spectrometry (CE-MS) - Principles and Applications (Hardcover)
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This monograph offers the reader a complete overview on both
principles and applications of CE-MS. Starting with an introductory
chapter on detection in CE, also related and more specialized
techniques such as electrophoretic and chromatographic
preconcentration are discussed. A special emphasis is put on CE-MS
interfaces, which are described in detail. In a separate chapter,
attention is paid to sheath-liquid interfacing. The developments
and possibilities of microchip CE-MS are also described.
Applications to all relevant areas are discussed in distinct
chapters, each written by experts in the respective fields. Besides
applications in pharmaceutical analysis and bioanalysis, recent
implementations in food science, forensic analysis, analysis of
intact proteins, metabolomics and proteomics are highlighted. MS is
a perfectly appropriate detection system for CE, as efficient
separation is coupled to sensitive and selection detection.
Moreover, MS can provide structure information on the separated
compounds. CE-MS has now been developed into a strong hyphenated
system complementary to LC-MS. This monograph is an unique source
of knowledge for everyone dealing with and interested in CE-MS.
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