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Animal Hematotoxicology - A Practical Guide for Toxicologists and Biomedical Researchers (Paperback)
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Animal Hematotoxicology - A Practical Guide for Toxicologists and Biomedical Researchers (Paperback)
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Hematology data from in vivo toxicology studies remains one of the
most predictive measures for human risk, as the same measurements
made in pre-clinical toxicology studies can be made in early
clinical trials. Covering the three main blood cell types -
erythrocytes, leukocytes and thrombocytes, this work is designed to
clarify topics for new entrants to the fields of laboratory animal
hematology and toxicology, especially those topics where the rules
for human hematology do not always apply. An entire chapter is
devoted to immunotoxicology, a scientific discipline that is
closely aligned with hematology. The text also addresses
pre-analytical and analytical variables that affect animal studies,
as these play a far more important part when interpreting data in
contrast to humans where many of these variables can be well
controlled or have less physiological effect. Information has been
collated from published papers, textbooks and unpublished data:
Readers are provided with key references to encourage further study
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