Driven by the widespread growth of proteomic practices, protein
separation techniques have been refined to minimize variability,
optimize particular applications, and adapt to user preferences in
the analysis of proteins.
Separation Methods in Proteomics provides a comprehensive
examination of all major separation techniques for proteomics
research.
Written as a compilation of hands-on methods exemplified by the
work of several recognized leaders in the field, this book may
serve as a guide for selection of the optimal separation strategies
to solve particular biological problems.
Recent progress in the development of robust analytical
techniques and instrumentation has created the need for good
quality biological samples that are subject to analysis.
Emphasizing the importance of sample preparation, the book explains
how proteomes can be divided into smaller, less complicated
"subproteomes" for individual analysis. It also highlights several
hybrid approaches that take into account protein interactions.
Including applications of the separation methods currently
employed in proteomic analyses for both clinical and basic
research, Separation Methods in Proteomics contains practical
information that can enhance the current and future endeavors of
scientists in proteomics, genomics, transcriptomics, biomarker
discovery, and drug discovery.
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