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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Computational Genetics and Genomics - Tools for Understanding Disease (Hardcover, 2005 ed.)
Loot Price: R4,276
Discovery Miles 42 760
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Computational Genetics and Genomics - Tools for Understanding Disease (Hardcover, 2005 ed.)
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Ultimately, the quality of the tools available for genetic analysis
and experimental disease models will be assessed on the basis of
whether they provide new information that generates novel
treatments for human disease. In addition, the time frame in which
genetic discoveries impact clinical practice is also an important
dimension of how society assesses the results of the significant
public financial investment in genetic research. Because of the
investment and the increased expectation that new tre- ments will
be found for common diseases, allowing decades to pass before basic
discoveries are made and translated into new therapies is no longer
acceptable. Computational Genetics and Genomics: Tools for
Understanding Disease provides an overview and assessment of
currently available and developing tools for genetic analysis. It
is hoped that these new tools can be used to identify the genetic
basis for susceptibility to disease. Although this very broad topic
is addressed in many other books and journal articles,
Computational Genetics and Genomics: Tools for Understanding
Disease focuses on methods used for analyzing mouse genetic models
of biomedically - portant traits. This volume aims to demonstrate
that commonly used inbred mouse strains can be used to model
virtually all human disea- related traits. Importantly, recently
developed computational tools will enable the genetic basis for
differences in disease-related traits to be rapidly identified
using these inbred mouse strains. On average, a decade is required
to carry out the development process required to demonstrate that a
new disease treatment is beneficial.
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