Explosive growth in the field of microsystem technology (MST)
has introduced a variety of promising products in major disciplines
from microelectronics to life sciences. Especially the life
sciences and health care business was, and is expected to be a
major market for MST products. Undoubtedly the merging of
biological sciences with micro- and nanoscience will create a
scientific and technological revolution in future.
Microminiaturization of devices, down to the nanoscale, approaching
the size of biological structures, will be a prerequisite for the
future success of life sciences. Bioanalytical and therapeutic
micro- and nanosystems will be mandatory for system biologists in
the long run, to obtain insight into morphology, the function and
the interactive processes of the living system. With such a deeper
understanding new and personalized drugs could be developed leading
to a revolution in life sciences. Today, microanalytical devices
are used in clinical analytics or molecular biology as gene chips.
In parallel, standard microbiomedical products are employed in the
intensive care and surgical theatre, mainly for monitoring and
implantation purposes. The gap between these two different
scientific fields will be closed, however, as soon as functional
micro devices can be produced, allowing a deeper view into the
function of cells and whole organisms.
Here, a new discipline evolved which focuses on microsystems for
living systems called "BIOMEMS." In this review at a glance the
exciting field of bio-microsystems, from their beginnings to
indicators of future successes are presented. It will also show
that a broad penetration of micro and nano technologies into
biology and medicine will be mandatory for future scientific and
new product development progress in life science.
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