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Genomics in the Cloud - Using Docker, GATK, and WDL in Terra (Paperback)
Loot Price: R1,482
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Genomics in the Cloud - Using Docker, GATK, and WDL in Terra (Paperback)
Expected to ship within 12 - 17 working days
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Data in the genomics field is booming. In just a few years,
organizations such as the National Institutes of Health (NIH) will
host 50+ petabytes-or over 50 million gigabytes-of genomic data,
and they're turning to cloud infrastructure to make that data
available to the research community. How do you adapt analysis
tools and protocols to access and analyze that volume of data in
the cloud? With this practical book, researchers will learn how to
work with genomics algorithms using open source tools including the
Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. With this
practical book, researchers will learn how to work with genomics
algorithms using open source tools including the Genome Analysis
Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera,
longtime custodian of the GATK user community, and Brian O'Connor
of the UC Santa Cruz Genomics Institute, guide you through the
process. You'll learn by working with real data and genomics
algorithms from the field. This book covers: Essential genomics and
computing technology background Basic cloud computing operations
Getting started with GATK, plus three major GATK Best Practices
pipelines Automating analysis with scripted workflows using WDL and
Cromwell Scaling up workflow execution in the cloud, including
parallelization and cost optimization Interactive analysis in the
cloud using Jupyter notebooks Secure collaboration and
computational reproducibility using Terra
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