The book summarizes our progress in understanding the receptor and
intracellular signaling mechanisms utilized by a family of proteins
called the semaphorins. Originally these protein were identified as
axon guidance cues important for the formation of nerve tracts but
now it is realized that semaphorins subserve several distinct
functions in a multitude of organ systems. The purpose of this book
is to summarize our knowledge and make it available as a useful and
comprehensive tool for the scientific community. This book will
both be interesting for people working in the field as well as
colleagues that work in other fields of science and would like to
learn more about semaphorins and associated signaling mechanisms.
All the latest techniques and results are summarized in this book
which covers the entire semaphorin field from neurosciences to
cardiovascular research and beyond. The strength of this book is
that it gives a very comprehensive overview of all our knowledge of
semaphorin biology and signaling and allows one to compare
semaphorin functions between different biological systems.
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