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Application of Muscle/Nerve Stimulation in Health and Disease (Hardcover, 2008 ed.)
Loot Price: R4,376
Discovery Miles 43 760
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Application of Muscle/Nerve Stimulation in Health and Disease (Hardcover, 2008 ed.)
Series: Advances in Muscle Research, 4
Expected to ship within 10 - 15 working days
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The first evidence that electrical changes can cause muscles to
contract was p- vided by Galvani (1791). Galvani's ideas about
'animal electricity' were explored during the 19th and 20th century
when it was firmly established that 'electricity' is one of the
most important mechanisms used for communication by the nervous
system and muscle. These researches lead to the development of ever
more soph- ticated equipment that could either record the
electrical changes in nerves and muscles, or elicit functional
changes by electrically stimulating these structures. It was indeed
the combination of these two methods that elucidated many of the
basic principles about the function of the nervous system.
Following these exciting findings, it was discovered that
electrical stimulation and the functions elicited by it also lead
to long-term changes in the properties of nerves and particularly
muscles. Recent findings help us to understand the mec- nisms by
which activity induced by electrical stimulation can influence
mature, fully differentiated cells, in particular muscles, blood
vessels and nerves. Electrically elicited activity determines the
properties of muscle fibres by activating a sequence of signalling
pathways that change the gene expression of the muscle. Thus,
elect- cal activity graduated from a simple mechanism that is used
to elicit muscle c- traction, to a system that could induce
permanent changes in muscles and modify most of its characteristic
properties.
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