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Carbohydrate Chemistry - Proven Synthetic Methods, Volume 2 (Paperback)
Loot Price: R2,173
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Carbohydrate Chemistry - Proven Synthetic Methods, Volume 2 (Paperback)
Series: Carbohydrate Chemistry: Proven Synthetic Methods
Expected to ship within 12 - 17 working days
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The second volume in the series Carbohydrate Chemistry: Proven
Synthetic Methods, Volume 2 offers a collection of synthetic
procedures valuable to the practice of synthetic carbohydrate
chemistry. The series takes an important and unique approach in
that all described procedures have been independently verified as
reliable and reproducible. With editors and contributors who are
highly respected scientists in the field, this book provides a
widely useful reference for both researchers and students,
exploring carbohydrate chemistry from both academic and industrial
points of view. The book begins with an introductory section that
offers tricks and tips collected by the series editor from many
years of experience working in carbohydrate laboratories. The
subsequent chapters present detailed protocols on both specific
synthetic transformations and the preparation of common synthetic
intermediates, with figures to aid in comprehension. Procedures are
described for regioselective benzylidene ring opening reactions,
oxidation reactions to provide uronic acids, stereoselective
alpha-glucosylation reactions, and more. Protocols for synthetic
intermediates of general utility include
3,4,6-tri-O-acetyl-d-galactal, phenyl 4,6-O-benzylidene-1-thio-
-d-mannopyranoside, 1,2-anhydro-3,4,6-tri-O-benzyl-
-d-mannopyranoside, and methyl N-acetylneuraminic acid, among many
others. Each chapter presents in-depth experimental descriptions
for the reported procedures, including reaction setup, reaction
conditions, work-up procedures, and purification protocols. The
chapters also provide detailed characterization of all products and
intermediates as well as copies of the 1H NMR and 13C NMR of the
described products and intermediates to indicate the purity of the
obtained materials and to serve as a valuable reference for future
practitioners. This book provides an important starting point to
reliably access synthetic carbohydrate materials and as such offers
a valuable resource for the synthetic organic chemistry community.
Through the streamlined access of well-defined products it provides
a thrust to the rapidly growing field of chemical glycobiology.
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