This volume provides updated information on epilepsy genes, on the
clinical picture of genetic epilepsies discovered so far, and on
conceptual advances in the complicated area of genotype-phenotype
correlations. Recent studies on monogenic epilepsies present new
insights into mechanisms whereby a mutation of a single gene,
coding for an ion channel, can result in a complex epileptic
phenotype. The analysis of genetically-determined epileptogenic
dysplasia is advancing our understanding of the role of genes in
controlling normal and pathological brain development. The
pathogenic mechanisms by which gene mutations determine progressive
myoclonus epilepsies offer critical opportunities to understand the
role of genetic factors in neurodegenerative phenome-na associated
with an even broader range of progressive epilepsy types. The
specialists who have contributed to this book are outstanding
international experts in their respective fields, ensuring first
and foremost that the reviews are of relevance to clinicians
dealing with epilepsy in their daily practice, as well as providing
the highest quality scientific information for biomedical research.
General
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