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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
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Introduction to Computational Proteomics (Hardcover)
Loot Price: R6,024
Discovery Miles 60 240
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Introduction to Computational Proteomics (Hardcover)
Series: Chapman & Hall/CRC Computational Biology Series
Expected to ship within 12 - 17 working days
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Introduction to Computational Proteomics introduces the field of
computational biology through a focused approach that tackles the
different steps and problems involved with protein analysis,
classification, and meta-organization. The book starts with the
analysis of individual entities and works its way through the
analysis of more complex entities, from protein families to
interactions, cellular pathways, and gene networks. The first part
of the book presents methods for identifying the building blocks of
the protein space, such as motifs and domains. It also describes
algorithms for assessing similarity between proteins based on
sequence and structure analysis as well as mathematical models,
such as hidden Markov models and support vector machines, that are
used to represent protein families and classify new instances. The
second part covers methods that investigate higher order structure
in the protein space through the application of unsupervised
learning algorithms, such as clustering and embedding. The book
also explores the broader context of proteins. It discusses methods
for analyzing gene expression data, predicting protein-protein
interactions, elucidating cellular pathways, and reconstructing
gene networks. This book provides a coherent and thorough
introduction to proteome analysis. It offers rigorous, formal
descriptions, along with detailed algorithmic solutions and models.
Each chapter includes problem sets from courses taught by the
author at Cornell University and the Technion. Software downloads,
data sets, and other material are available at biozon.org
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