As the population ages there is an increasing concern amongst the
population about the aging knee. Osteoarthritis as it iscalled
affects population without distinction of caste,creed,nationality
and gender. Understanding the pathogenesis of this debilitating
disease would certainly help in the proper management. Diagnosis is
usually never an issue as it can be diagnosed by the cardinal signs
of chronic pain, stiffness, crepitations and varus deformities.
Radiologically one finds decrease in joint space, osteophytes,
subchondral sclerosis, subchondral cysts, loose bodies amongst
others. Comprehensive medical research globally points out to
various newer mechanisms in the synthesis of pain in OA knee. The
treatment options are very many ranging from reassuance till
complex replacement surgeries which are so common these days. A
comprehensive discussion of various pathogenesis theories are
discussed and newer concepts of medical management are suggested
keeping the patients compliance as one of the important parameters.
These deliberations should lead to further research in various
conservative management options for this debilitating condition.
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