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Books > Medicine > Clinical & internal medicine > Hepatology
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Pregnancy, Sex Hormones and the Liver (Hardcover, 1996 ed.)
Loot Price: R5,329
Discovery Miles 53 290
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Pregnancy, Sex Hormones and the Liver (Hardcover, 1996 ed.)
Series: Falk Symposium, 89
Expected to ship within 18 - 22 working days
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Pregnancy is the main determinant of some liver diseases in humans:
acute fatty liver of pregnancy, cholestasis of pregnancy, and acute
liver failure in toxaemia of pregnancy. Pregnancy also modifies the
natural history of other more common hepatobiliary diseases, such
as cholesterol gallstones. Sex hormones (mainly oestrogens,
progesterone and/or some of its metabolites) and prolactin are
considered responsible for these pathological consequences and they
also appear to be influential in the outcome of several other
hepatobiliary disorders, in both sexes and all ages. Although these
disorders and their hormonal interrelations have been clinically
well characterized, their pathogenesis remains obscure from the
biomolecular point of view. In recent years, novel approaches using
new technologies have improved our understanding of hormone actions
and metabolism, hormone receptors, metabolic pathways and their
interrelations with closely related molecules, such as bile acids.
This book, the proceedings of the 89th Falk Symposium, held in
Santiago, Chile, 10-11 November, 1995, will help research
scientists and clinicians to review basic and clinical aspects of
these interactions, in order to stimulate biomedical research in a
relevant and exciting area.
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