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Cellular Quiescence - Methods and Protocols (Hardcover, 1st ed. 2018)
Loot Price: R3,722
Discovery Miles 37 220
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Cellular Quiescence - Methods and Protocols (Hardcover, 1st ed. 2018)
Series: Methods in Molecular Biology, 1686
Expected to ship within 12 - 17 working days
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Total price: R3,742
Discovery Miles: 37 420
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This detailed volume explores methods and protocols that aim to
increase our understanding of how cells enter a quiescent state
during homeostasis and how cells exit quiescence and re-enter
differentiating cell divisions to restore damaged tissues,
essential for developing new approaches in regenerative medicine in
the future. The chapters in this book were designed to address
cellular quiescence in prokaryote and eukaryote organisms,
detection of quiescence (Hoechst/pyronin Y, FUCCI, CFSE, BrdU,
H2B-GFP, CyTOF), quiescence in stem cells (skin, intestinal,
neuronal, hematopoietic), genomic regulation (gene expression,
transcription factors, lncRNA, RNA methylation), as well as
analysis of the heterogeneity of quiescence by computer modeling.
Written for the highly successful Methods in Molecular Biology
series, chapters include introductions to their respective topics,
lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
practical, Cellular Quiescence: Methods and Protocols offers a
broad view of basic and cutting-edge technology to inspire research
in this emerging field of cell biology.
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