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Control of Gene Expression by Catecholamines and the Renin-Angiotensin System (Paperback, Softcover reprint of the original 1st ed. 2000)
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Control of Gene Expression by Catecholamines and the Renin-Angiotensin System (Paperback, Softcover reprint of the original 1st ed. 2000)
Series: Developments in Molecular and Cellular Biochemistry, 33
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The special issue of Molecular and Cellular Biochemistry focuses on
`Control of Gene Expression by Catecholamines and the
Renin-Angiotensin System' in health and disease. In recent years,
great progress has been made in the understanding of catecholamine
and angiotensin II modulated gene expression. There is also
increasing evidence that catecholamine and angiotensin II induced
cellular injury not solely arises from classical pathways but also
from a perturbed gene expression. Taking into account that
catecholamines and angiotensin II are vital for a balanced gene
expression of many cells, the intriguing possibility arises that
various disease are initiated or aggravated by such an imbalance.
Catecholamine and angiotensin II influences can be in excess
arising from, for example, hypercaloric food intake or psychosocial
stress. During early progression of heart failure, sympathetic
activity and angiotensin II influences also become increased. Due
to beta-adrenergic receptor downregulation, depressed catecholamine
influences are expected in the final stage of heart failure. An
imbalanced influence of catecholamines and angiotensin II on gene
expression leads to disordered molecular structures of the cell and
an impaired cell function. This focused issue is organized into
chapters concentrating on catecholamines, angiotensin II, and the
interaction between catecholamines and angiotensin II. Basic
biochemical processes are covered in detail and the potential of
these pathways for explaining chronic diseases associated with
excess catecholamine and angiotensin II influences should become
apparent. It is hoped that this focussed issue triggers novel
research into the development of drugs that are targeted at
diseases characterized by an imbalanced gene expression involving
catecholamines and angiotensin II.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Developments in Molecular and Cellular Biochemistry, 33 |
Release date: |
October 2012 |
First published: |
2000 |
Editors: |
Heinz Rupp
• Bernhard Maisch
|
Dimensions: |
280 x 210 x 13mm (L x W x T) |
Format: |
Paperback
|
Pages: |
239 |
Edition: |
Softcover reprint of the original 1st ed. 2000 |
ISBN-13: |
978-1-4613-6955-4 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Biochemistry >
General
|
LSN: |
1-4613-6955-X |
Barcode: |
9781461369554 |
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