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Simultaneous UV Estimation of Antihypertesive Drugs (Paperback)
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Simultaneous UV Estimation of Antihypertesive Drugs (Paperback)
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A new, simple, accurate, precise and reproducible UV
spectrophotometric method is being developed for the simultaneous
estimation of amlodipine besylate, olmesartan medoxomil and
hydrochlorthiazide in tablet dosage form. The stock solutions were
prepared in methanol. The max for amlodipine besylate, olmesartan
medoxomil and hydrochlorthiazide were 238.5nm, 256.5nm and 271.5nm
respectively. The amlodipine besylate, olmesartan medoxomil and
hydrochlorthiazide obeyed Beer's law in concentration range of
5-25ug/ml, 6-30ug/ml and 5-25ug/ml respectively. Results of
analysis of simultaneous equation method were analyzed and
validated for various parameters according to ICH guidelines.
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