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Perspectives of Stem Cells - From tools for studying mechanisms of neuronal differentiation towards therapy (Paperback, 2010 ed.)
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Perspectives of Stem Cells - From tools for studying mechanisms of neuronal differentiation towards therapy (Paperback, 2010 ed.)
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Stem cells are fascinating cell types. They can replicate
themselves forever while retaining the potential to generate
progeny with speci?c functions. Because of these special
properties, stem cells have been subjects of intensive
investigation, from understanding basic mechanisms underlying
tissue generation, to modeling human diseases, to application for
cell replacement therapy. Stem cells come in different forms. For
example, mouse embryonic stem cells can general all cell types in a
body, either in a dish or when put back into mouse embryos. On the
other hand, neural stem cells in the adult brain generate neurons
and glia cells that contribute to the brain's plasticity. Rapid
progress has been made in the stem cell ?eld with discov- ies
published in a record speed. A quick Pubmed search has returned
2789 hits for "embryonic stem cells" and 815 hits for "adult neural
stem cells/neurogenesis" in the year 2008 alone. It remains a
taunting task for all who are interested in stem cells to keep up
with rapidly accumulating literatures. The "Perspectives of Stem
Cells" by a truly international team of experts provides a timely
and invaluable highlight of the stem cell ?eld gearing toward
future therapeutic applications in the nervous system. Stem cells
with neural potentials have attracted a lot of attention because of
their promise for cell replacement therapy, ranging from
degenerative neurological dis- ders to spinal cord injuries.
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