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Immunomodulation by Bacteria and Their Products (Paperback, 1981 ed.)
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Immunomodulation by Bacteria and Their Products (Paperback, 1981 ed.)
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It is almost axiomatic that an explosive increase in knowledge and
interest concerning host immune defense mechanisms and the immune
response system in general is occurring. Many new developments are
evident at the interphase between the areas of immunology,
infectious diseases, and host defenses to microorganisms. It is now
widely rec ognized that a functioning host immune defense system
consists of a variety of lymphoid cells. These include effector and
affector cells consisting of both Band T cells and their progeny.
Mononuclear phago cytes which are widely distributed throughout the
body are also intimately involved in these processes. These cells
are involved not only in the clearance of particulate matter
including bacteria, viruses and fungi, but also presumably in host
defense against neo plasia. Among the many triumphs of the
biological revolution over the past decade or so is the rapidly
developing understanding of how these cells and their products,
including antibody, lymphokines, monokines, etc., function and
interact. It is now recognized that although the immune defense
system is involved in defense against infectious agents, it is also
now be coming quite clear that many infectious agents, including
bacteria, viruses and fungi, as well as their products, can
interact with the immune response system. For example, it has been
long recognized that many of the "adjuvants" which enhance the
immune responses in nonspecific ways are derived from
microorganisms. Microbial products have marked effects on the
immume response system."
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