IgM and Its Receptors and Binding Proteins (Hardcover, 1st ed. 2017)

This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fc /R), and Fc receptor for IgM only (FcR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Current Topics in Microbiology and Immunology, 408
Release date:	November 2017
First published:	2017
Editors:	Hiromi Kubagawa • Peter D. Burrows
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	117
Edition:	1st ed. 2017
ISBN-13:	978-3-319-64524-7
Categories:	Books > Medicine > Clinical & internal medicine > Rheumatology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General Promotions
LSN:	3-319-64524-2
Barcode:	9783319645247

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