Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease (Paperback, Softcover reprint of the original 1st ed. 2015)

Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Current Topics in Behavioral Neurosciences, 22
Release date:	October 2016
First published:	2015
Editors:	Hoa Huu Phuc Nguyen • M. Angela Cenci
Dimensions:	235 x 155 x 21mm (L x W x T)
Format:	Paperback
Pages:	397
Edition:	Softcover reprint of the original 1st ed. 2015
ISBN-13:	978-3-662-52412-1
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > General
LSN:	3-662-52412-0
Barcode:	9783662524121

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