Cell signalling lies at the heart of many biological processes
and currently is the focus of intense research interest. In
multicellular organisms, it is central to how different types of
cell communicate with each other and how they detect and respond to
extracellular signals. Intercellular communication is vital to
single-celled organisms as well, allowing them to respond to
environmental cues and signals.
To date, much of the understanding of signalling mechanisms has
come from research on specific cell types (eg mouse lymphocyte and
cardiomyocyte) or on organisms in which communication systems such
as nervous and endocrine systems are well established. This volume
therefore aims to 'fill the gap' by concentrating on 'simple
organisms' where the elements of those signalling systems first
evolved. Many of the groups covered contain important pathogens or
parasites, and the potential for manipulating signalling pathways
for therapeutic intervention will be highlighted.
General
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