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Critical Appraisal of Epidemiological Studies and Clinical Trials (Hardcover, 3rd Revised edition)
Loot Price: R5,328
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Critical Appraisal of Epidemiological Studies and Clinical Trials (Hardcover, 3rd Revised edition)
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This book presents a logical system of critical appraisal, to allow
readers to evaluate studies and to carry out their own studies more
effectively. This system emphasizes the central importance of cause
and effect relationships. Its great strength is that it is
applicable to a wide range of issues, and both to intervention
trials and observational studies. This system unifies the often
different approaches used in epidemiology, health services
research, clinical trials, and evidence-based medicine, starting
from a logical consideration of cause and effect. The author's
approach to the issues of study design, selection of subjects,
bias, confounding, and the place of statistical methods has been
praised for its clarity and interest. Systematic reviews,
meta-analysis, and the applications of this logic to evidence-based
medicine, knowledge-based health care, and health practice and
policy are discussed. Current and often controversial examples are
used, including screening for prostate cancer, publication bias in
psychiatry, public health issues in developing countries, and
conflicts between observational studies and randomized trials.
Statistical issues are explained clearly without complex
mathematics, and the most useful methods are summarized in the
appendix. The final chapters give six applications of the critical
appraisal of major studies: randomized trials of medical treatment
and prevention, a prospective and a retrospective cohort study, a
small matched case-control study, and a large case-control study.
In these chapters, sections of the original papers are reproduced
and the original studies placed in context by a summary of current
developments.
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