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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Epidemiology and Control of Neural Tube Defects (Hardcover)
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Epidemiology and Control of Neural Tube Defects (Hardcover)
Series: Monographs in Epidemiology and Biostatistics, 20
Expected to ship within 12 - 17 working days
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Neural tube defects, spina bifida, anencephalus, and
encephalocoele, are among the commonest severe congenital
abnormalities in most countries. The last decade has seen many
advances, including the use of antenatal diagnosis by chemical and
ultrasound methods, population screening, and many new findings in
epidemiology, culminating in the demonstration of the protective
effect of folic acid on recurrences. The progress in both antenatal
diagnosis and in aetiological research on neural tube defects has
been particularly dramatic, and may well anticipate developments in
regard to other congenital abnormalities. Primary prevention now
appears as an attainable goal. This book presents a critical review
of the extensive findings of epidemiological studies, discusses
several methodological issues of wider relevance such as
ascertainment, seasonal variation, ethical and legal issues. As
well as providing a unique resource in regard to neural tube
defects, much of the material is relevant to those with wider
interests in the prevention, antenatal diagnosis, and control of
major diseases.
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