In 1989 Michael Bishop and Harold Varmus were awarded the Nobel
Prize for their discovery that normal genes under certain
conditions can cause cancer. In this book, Bishop tells us how he
and Varmus made their momentous discovery. More than a lively
account of the making of a brilliant scientist, "How to Win the
Nobel Prize" is also a broader narrative combining two major and
intertwined strands of medical history: the long and ongoing
struggles to control infectious diseases and to find and attack the
causes of cancer.
Alongside his own story, that of a youthful humanist evolving
into an ambivalent medical student, an accidental microbiologist,
and finally a world-class researcher, Bishop gives us a fast-paced
and engrossing tale of the microbe hunters. It is a narrative
enlivened by vivid anecdotes about our deadliest microbial
enemies--the Black Death, cholera, syphilis, tuberculosis, malaria,
smallpox, HIV--and by biographical sketches of the scientists who
led the fight against these scourges.
Bishop then provides an introduction for nonscientists to the
molecular underpinnings of cancer and concludes with an analysis of
many of today's most important science-related
controversies--ranging from stem cell research to the attack on
evolution to scientific misconduct. "How to Win the Nobel Prize"
affords us the pleasure of hearing about science from a brilliant
practitioner who is a humanist at heart. Bishop's perspective will
be valued by anyone interested in biomedical research and in the
past, present, and future of the battle against cancer.
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