Polycystic Kidney Disease (Hardcover)

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features Explores the role of cilia in polycystic kidney disease Focuses on myriad state-of-the-art methods and techniques Reviews specific mutations integral to this autosomal genetic disease Includes discussions of model systems

General

Imprint:	Crc Press
Country of origin:	United Kingdom
Series:	Methods in Signal Transduction Series
Release date:	November 2019
First published:	2020
Authors:	Jinghua Hu • Yong Yu
Dimensions:	234 x 156 x 26mm (L x W x T)
Format:	Hardcover
Pages:	346
ISBN-13:	978-1-138-60389-9
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Clinical & internal medicine > Endocrinology > General Books > Medicine > Clinical & internal medicine > Renal medicine > General Books > Medicine > Other branches of medicine > Pathology > Cytopathology
LSN:	1-138-60389-9
Barcode:	9781138603899

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