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Books > Medicine > Clinical & internal medicine > Renal medicine
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Polycystic Kidney Disease (Hardcover)
Loot Price: R3,501
Discovery Miles 35 010
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Polycystic Kidney Disease (Hardcover)
Series: Methods in Signal Transduction Series
Expected to ship within 12 - 17 working days
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This volume focuses on the investigatory methods applied to
autosomal dominant polycystic kidney disease (ADPKD), one of the
most common human genetic diseases. ADPKD is caused by mutations in
PKD1 and TRPP2, two integral membrane proteins that function as
receptor/ion channels in primary cilia of tubular epithelial cells.
Thus, ADPKD belongs to ciliopathies, a group of disorders caused by
abnormal cilia formation or function. This proposed book will cover
the state-of-the-art methods ranging from molecular biology,
biochemistry, electrophysiology, to tools in model animal studies.
Key Features Explores the role of cilia in polycystic kidney
disease Focuses on myriad state-of-the-art methods and techniques
Reviews specific mutations integral to this autosomal genetic
disease Includes discussions of model systems
General
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