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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Metabolism

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Insulin Resistance - Symptoms, Causes & Treatment (Hardcover, New) Loot Price: R4,882
Discovery Miles 48 820
You Save: R1,301 (21%)
Insulin Resistance - Symptoms, Causes & Treatment (Hardcover, New): Jocelyn Moliere, Lance Gauthier

Insulin Resistance - Symptoms, Causes & Treatment (Hardcover, New)

Jocelyn Moliere, Lance Gauthier

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List price R6,183 Loot Price R4,882 Discovery Miles 48 820 | Repayment Terms: R458 pm x 12* You Save R1,301 (21%)

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Insulin resistance (IR) and elevated blood pressure are two key features of the metabolic syndrome, which play an important role in the development of secondary cardiovascular complications. In this book, the effects of insulin resistance on the various vasoactive pathways are explored, which affect the equilibrium between vascular relaxation and constriction. Furthermore, the interaction between oestrogen, testosterone and insulin signalling-dependent changes in vascular reactivity and blood pressure are discussed. Also addressed in this book are the mechanisms underlying reciprocal relationships between insulin secretion, insulin resistance and inflammation in the pathological state and in its subsequent improvement. Moreover, the current concepts in understanding the underlying risk factors contributing to insulin resistance are examined, focusing on the role of magnesium deficiency that emerges as potential pathogenic key related with decreasing insulin sensitivity. In addition, it is widely accepted that metabolic syndrome is related to cardiovascular disease and that insulin resistance is one of the causes of metabolic syndrome. The authors discuss thiazolidinediones (TZDs), a class of antidiabetes agents, as a means to improve endothelial dysfunction, prevent atherosclerosis, and significantly reduce the risk of cardiovascular disease.

General

Imprint: nova science publishers
Country of origin: United States
Release date: 2012
First published: 2010
Editors: Jocelyn Moliere • Lance Gauthier
Dimensions: 180 x 260 x 22mm (L x W x T)
Format: Hardcover
Pages: 273
Edition: New
ISBN-13: 978-1-60876-829-5
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Metabolism
LSN: 1-60876-829-5
Barcode: 9781608768295

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