Considering the extensive applications that have been discovered
for naphthoquinone-triazole hybrids in the search for new bioactive
molecules, Heterocycles: Synthesis, Reactions and Applications
first comprehensively addresses recent synthetic strategies for
their preparation. The authors highlight recent developments in
reaction strategies for the synthesis of dihydro-, tetrahydro-,
pyrano-pyrans and tetrahydrofurans and their applications in
natural product synthesis. The important structural features of
heterocyclic compounds are reviewed, as well as their deviation
from the planar configuration in the form of puckering or buckling,
and methods of suppression. The closing study explores the reaction
of azides with Grignard or organolithium reagents in an inter- or
intramolecular fashion to form linear or cyclic triazene
intermediates, respectively.
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