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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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Lead Generation - Methods, Strategies and Case Studies (Hardcover)
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Lead Generation - Methods, Strategies and Case Studies (Hardcover)
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In this comprehensive two-volume resource on the topic senior lead
generation medicinal chemists present a coherent view of the
current methods and strategies in industrial and academic lead
generation. This is the first book to combine both standard and
innovative approaches in comparable breadth and depth, including
several recent successful lead generation case studies published
here for the first time. Beginning with a general discussion of the
underlying principles and strategies, individual lead generation
approaches are described in detail, highlighting their strengths
and weaknesses, along with all relevant bordering disciplines like
e.g. target identification and validation, predictive methods,
molecular recognition or lead quality matrices. Novel lead
generation approaches for challenging targets like DNA-encoded
library screening or chemical biology approaches are treated here
side by side with established methods as high throughput and
affinity screening, knowledge- or fragment-based lead generation,
and collaborative approaches. Within the entire book, a very strong
focus is given to highlight the application of the presented
methods, so that the reader will be able to learn from real life
examples. The final part of the book presents several lead
generation case studies taken from different therapeutic fields,
including diabetes, cardiovascular and respiratory diseases,
neuroscience, infection and tropical diseases. The result is a
prime knowledge resource for medicinal chemists and for every
scientist involved in lead generation.
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