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Epigenetic Biomarkers and Diagnostics (Hardcover)
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Epigenetic Biomarkers and Diagnostics (Hardcover)
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Epigenetic Biomarkers and Diagnostics comprises 31 chapters
contributed by leading active researchers in basic and clinical
epigenetics. The book begins with the basis of epigenetic
mechanisms and descriptions of epigenetic biomarkers that can be
used in clinical diagnostics and prognostics. It goes on to discuss
classical methods and next generation sequencing-based technologies
to discover and analyze epigenetic biomarkers. The book concludes
with an account of DNA methylation, post-translational
modifications and noncoding RNAs as the most promising biomarkers
for cancer (i.e. breast, lung, colon, etc.), metabolic disorders
(i.e. diabetes and obesity), autoimmune diseases, infertility,
allergy, infectious diseases, and neurological disorders. The book
describes the challenging aspects of research in epigenetics, and
current findings regarding new epigenetic elements and modifiers,
providing guidance for researchers interested in the most advanced
technologies and tested biomarkers to be used in the clinical
diagnosis or prognosis of disease.
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