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Books > Medicine > Other branches of medicine > Pathology > Gross pathology
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Molecular Diagnosis of Cancer - Methods and Protocols (Paperback, Softcover reprint of hardcover 2nd ed. 2004)
Loot Price: R3,166
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Molecular Diagnosis of Cancer - Methods and Protocols (Paperback, Softcover reprint of hardcover 2nd ed. 2004)
Series: Methods in Molecular Medicine, 97
Expected to ship within 10 - 15 working days
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We are currently experiencing a fundamental shift in the way in
which we approach the characterization of cancer. Never before has
the make up of cancer tissues and individual cells been so
exhaustively researched and char- terized. We are now capable of
producing molecular "fingerprints" that ch- acterize the expression
of all known and unknown genes within tumors and their surrounding
tissues. More than 30,000 different genes may be measured in each
patient's tumor in a single experiment. Simultaneously, novel
therapies that exploit the molecular roadmap have been developed
and are now being offered to patients. These novel agents, such as
Glivec, Herceptin, Iressa, and others, specifically target
individual genes within tumors and can produce d- matic responses
in some patients. These drugs are only the forerunners of a coming
tidal wave of novel therapeutics that individually target specific
m- ecules within cancer cells-more than 300 such agents are
currently in phase I or II clinical trials. This is an exciting
time for cancer specialists and patients alike. However, if we have
learned anything from the past 50 or more years of research into
cancer, it is that Lord Beaverbrook, in founding the British
national health service in the 1950s, was frighteningly prescient
when he defined the primary goal of health care to be "Diagnosis,
Diagnosis, Diag- sis. " Now, more than ever, it is essential that
appropriate diagnostic methods and approaches are applied to the
selection of patients for treatment.
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