Statistics in Clinical Vaccine Trials (Paperback, 2011 ed.)

This monograph offers well-founded training and expertise on the statistical analysis of data from clinical vaccine trials, i.e., immunogenicity and vaccine field efficacy studies. The book's scope is practical rather than theoretical. It opens with two introductory chapters on the immunology of vaccines to provide readers with the necessary background knowledge. It then continues with an in-depth exploration of the statistical methodology. Many real-life examples and SAS codes are presented, making application of the methods straightforward. Topics discussed include maximum likelihood estimation for censored antibody titers, ANCOVA for antibody values, analysis of equivalence and non-inferiority immunogenicity trial data, analysis of data from vaccine field efficacy trials (including data from studies with recurrent infection data), fitting protection curves to data of challenge or field efficacy studies, and the analysis of vaccine safety data.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Release date:	October 2014
First published:	2011
Authors:	Jozef Nauta
Dimensions:	235 x 155 x 16mm (L x W x T)
Format:	Paperback
Pages:	153
Edition:	2011 ed.
ISBN-13:	978-3-642-44191-2
Categories:	Books > Science & Mathematics > Mathematics > Probability & statistics
LSN:	3-642-44191-2
Barcode:	9783642441912

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