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Polymyalgia Rheumatica and Giant Cell Arteritis (Hardcover, 3rd ed. 2017)
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Polymyalgia Rheumatica and Giant Cell Arteritis (Hardcover, 3rd ed. 2017)
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This book, now in an extensively updated and expanded third
edition, offers important insights into polymyalgia rheumatica
(PMR) and giant cell arteritis (GCA), providing an overview of
their pathophysiology, genetics, immunology, and endocrinological
mechanisms but above all presenting the state of the art in
diagnosis and treatment. Both PMR and GCA are diseases of advanced
age. Early diagnosis and treatment can save one of the most
precious senses - vision. In this book, the role of imaging
techniques is thoroughly examined, with particular attention to
ultrasonography and FDG PET. All aspects of management of both
diseases are discussed, including the current use of
glucocorticoids, the efficacy of modern biological treatment, such
as infliximab, tocilizumab, and rituximab, and the available
monitoring tools. Diagnostic criteria for PMR and GCA are outlined,
with discussion of differential diagnosis. Among the other topics
addressed are disease classification, the histopathology of GCA,
the ACR criteria for temporal arteritis, the value of temporal
artery biopsy in GCA, serum cytokine profiles, chronobiology, and
sine syndromes. The reader will find that the book aids in
achieving early diagnosis and providing faster and more effective
disease management. General readers with an interest in
rheumatology, internal medicine, ophthalmology and gerontology will
find this book particularly valuable.
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