It is hardly necessary to define the concept of receptors to
readers of this series, but it should be borne in mind that in
several instances receptors are undefined entities, whose molecular
details remain to be established. On the other hand the ligand,
which recognizes the receptors, has been identified and
characterized in most cases. The current interest in the structure
and function of biological membranes gives great expectations that
we may understand in the near future the details of ligand-receptor
interaction. This interaction involves two defined steps: the
first, usually referred to as recognition, is followed by the
second step, transduction, in which the ligand-receptor interaction
is translated by the cell into a biochemical action. The present
two volumes which cover prokaryotic and eukaryotic virus receptors,
have been published together in order to illustrate the specificity
of virus receptor recognition which appears to be a guiding
principle for both bacteria and higher cells. The identification
and characterization of the receptors for phages of gram-negative
bacteria has to a large extent relied on the genetic tech niques
available for these organisms. In a similar way the availability of
genetic systems has also clarified the interrelationship between
animal retrovirus receptors even if the molecular structure remains
to be determined. The paucity of defined genetic systems may
therefore explain part of our ignorance concerning the mole cular
details of virus receptors on human cells and possibly also on
gram-positive bacteria."
General
Imprint: |
Springer
|
Country of origin: |
Netherlands |
Series: |
Receptors and Recognition |
Release date: |
March 2013 |
First published: |
1981 |
Editors: |
K. Longberg-Holm
|
Dimensions: |
235 x 155 x 12mm (L x W x T) |
Format: |
Paperback
|
Pages: |
217 |
Edition: |
Softcover reprint of the original 1st ed. 1981 |
ISBN-13: |
978-9401180245 |
Categories: |
Books >
Reference & Interdisciplinary >
Interdisciplinary studies >
General
|
LSN: |
9401180245 |
Barcode: |
9789401180245 |
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