A Focused, State-of-the-Art Overview of This Evolving Field
Presents Various Techniques for Glycoinformatics The development
and use of informatics tools and databases for glycobiology and
glycomics research have increased considerably in recent years. In
addition to accumulating well-structured glyco-related data,
researchers have now developed semi-automated methods for the
annotation of mass spectral data and algorithms for capturing
patterns in glycan structure data. These techniques have enabled
researchers to gain a better understanding of how these complex
structures affect protein function and other biological processes,
including cancer. One of the few up-to-date books available in this
important area, Glycome Informatics: Methods and Applications
covers all known informatics methods pertaining to the study of
glycans. It discusses the current status of carbohydrate databases,
the latest analytical techniques, and the informatics needed for
rapid progress in glycomics research. Providing an overall
understanding of glycobiology, this self-contained guide focuses on
the development of glycome informatics methods and current problems
faced by researchers. It explains how to implement informatics
methods in glycobiology. The author includes the required
background material on glycobiology as well as the mathematical
concepts needed to understand advanced mining and algorithmic
techniques. She also suggests project themes for readers looking to
begin research in the field.
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