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Reproductive Immunology (Paperback, 1997)
Loot Price: R2,844
Discovery Miles 28 440
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Reproductive Immunology (Paperback, 1997)
Series: Current Topics in Microbiology and Immunology, 222
Expected to ship within 10 - 15 working days
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Discrimination of self from nonself is the major function of the
immune system and understanding the mechanism(s) involved a main
employer of immunologists. Hence, the age-old puzzle of why a fetus
that contains a panel of major histocompatibility (MHC) antigens
derived from its mother and its father is not rejected
(spontaneously aborted) by lymphocytes from its mother who should
theoretically recognize foreign MHC molecules from the father has
remained of great interest. This dilemma has enticed immunologists
and developmental biologists for many years. This volume was
created to present the information currently on hand in this
subject to the scientific public. The guest editor, Professor Lars
Olding, has a long and distinguished history of contributions in
this field, having been one of the main propo nents of the argument
that lymphocytes from the fetus play an active role in this process
by suppressing lymphocytes from the mother from proliferating and
thereby acting as killer cells. His work has defined the phenomenon
and identified suppressor molecules (factors) involved in the
process. In a different but related chapter, Margareta Unander
extends such observations to the clinical study of women with
repeated "habitual" mIS carriages."
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