Characterization of Gene and Protein Structure.- Biosynthesis and
Assembly of the Factor VIII-von Willebrand Factor Complex.- Factor
IX: Gene Structure and Protein Synthesis.- Antithrombin III
Genetics, Structure and Function.- Interactions Between the
Functional Domains of Antithrombin III.- Protein C: Gene Structure
and Protein Synthesis.- Structural and Functional Properties of
Protein C.- Molecular Defects Affecting Hemostasis.- Molecular
Defects in Hemophilia A.- Molecular Defects in Hemophilia B.-
Molecular Defects in Human Antithrombin III Deficiency.- The
Biologic Impact of Hereditary Defects that Cause Thrombosis.-
Protein Production by Recombinant Technology.- Factors Limiting
Expression of Secreted Proteins in Mammalian Cells.- Synthesis of
Biologically Active Vitamin K-Dependent Coagulation Factors.- The
Expression of Therapeutic Proteins in Transgenic Animals.- Clinical
use of Proteins Produced by Recombinant Technology.- The Use of
Animal Models to Evaluate Proteins Produced by Recombinant
Technology.- Experiences with Recombinant Factor VIIa in
Hemophiliacs.- Clinical Trials of Factor VIII Produced by
Recombinant Technology.- Clinical Trials of Recombinant Factor
VIII.- Concluding Overview.- The Impact of Recombinant Technologies
in Understanding Plasma Proteins Important for Hemostasis and
Thrombosis.- Contributors.
General
Imprint: |
Kluwer Academic / Plenum Publishers
|
Country of origin: |
Netherlands |
Series: |
Advances in Experimental Medicine and Biology |
Release date: |
May 1991 |
First published: |
1991 |
Volume editors: |
Leon W. Hoyer
• William N. Drohan
|
Dimensions: |
260mm (L) |
Format: |
Hardcover
|
Pages: |
248 |
Edition: |
New |
ISBN-13: |
978-0-306-43893-6 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Haematology
|
LSN: |
0-306-43893-3 |
Barcode: |
9780306438936 |
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