Mass Spectroscopy Imaging (MSI) has emerged as an enabling
technique to provide insight into the molecular entities within
cells, tissues and whole-body samples and to understand inherent
complexities within biological metabolomes. In "Mass
""Spectrometry"" Imaging of Small Molecules"" Methods and
Protocols," experts in the MSI field present techniques for 2D and
3D visualization and quantification of a wide array of small
molecular species present in biologically relevant samples.
Chapters provide detailed operational instructions from sample
preparation to method selection, from comparative quantification to
structural identification and from data collection to visualization
of small molecule mapping in complex samples. Written in the
successful "Methods in Molecular Biology" series format, chapters
include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily
reproducible protocols and notes on troubleshooting and avoiding
known pitfalls.
Authoritative and easily accessible, "Mass ""Spectrometry""
Imaging of Small Molecules"" Methods and Protocols" aims to bring
the rapidly maturing methods of metabolic imaging to life science
researchers and to minimize technical intimidation in adapting new
technological platforms in biological research.
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