This new volume of Methods in Enzymology continues the legacy of
this premier serial with quality chapters authored by leaders in
the field. This volume covers research methods providing a a
theoretical overview on metabolic alterations of cancer cells and a
series of protocols that can be employed to study oncometabolism,
in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic
changes when compared to their normal counterparts, owing to both
genetic and epigenetic alterations. Although such a metabolic
rewiring has recently been indicated as "yet another" general
hallmark of cancer, accumulating evidence suggests that the
metabolic alterations of each neoplasm rather represent a molecular
signature that intimately accompanies, and hence cannot be severed
from, all facets of malignant transformation.
Continues the legacy of this premier serial with quality chapters
authored by leaders in the fieldCovers research methods in
biomineralization scienceContains sections on such topics providing
a a theoretical overview on metabolic alterations of cancer cells
and a series of protocols that can be employed to study
oncometabolism, in vitro, ex vivo and in vivo."
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