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Heterocyclic Polymethine Dyes - Synthesis, Properties and Applications (Hardcover, 2008 ed.)
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Heterocyclic Polymethine Dyes - Synthesis, Properties and Applications (Hardcover, 2008 ed.)
Series: Topics in Heterocyclic Chemistry, 14
Expected to ship within 10 - 15 working days
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This treatise pertains to dyes composed of a central polymethine
moiety and two cyclic terminal subunits. The polymethine linker can
be unsubstituted or substituted, and at least one terminal subunit
is a heterocyclic system. The classes of compounds reviewed range
from classical cyanines, ?rst s- thesized in the 1850s, to
hemicyanines, to styryl dyes, to merocyanines, to
coumarinpolymethines, andtosquarylium dyesthatweresynthesized
forthe ?rst time in the 1960s. These structurally diverse classes
of compounds have one commondenominator, namely electronconjugation
that involves the t-
minalheterocyclic/aromaticsubunitsandthecentralpolymethinelinkerofthe
molecule. Such conjugated molecules show absorption and ?uorescence
that are a function of the structure of the three moieties. By
changing the length and substitution of the polymethine linker
and/or the structures of the t- minal moieties, molecules can be
designed with absorption and ?uorescence ranging from the blue
visible region (> 400nm) to the near-infrared region (>
700nm) of the electromagnetic spectrum. The synthetic developments
of the last decade are reviewed and references to older but
important work are provided tohelpdesignadye ofinterest fora
desired speci?c application. It is
the?uorescencepropertiesthataremostimportantforalargearrayofmodern
applications of the dyes, especially in biotechnology. Some of the
applications are clearly visible from the titles of the individual
chapters, and additional
featurescanbefounduponinspectionofthecorrespondingtablesofcontents.
The subject index should be consulted for other properties and
applications of the dyes that could not be elaborated on
extensively in this relatively short reviewbook.
Theauthorstookexcellentcareofsuchinformationbyproviding leading
references on the additional subjects. I wish to thank the authors
for their outstanding contributions. Thanks are also due to Ms.
Birgit Kollmar- ThoniofSpringerandMs.
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