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Invertebrate Immune Responses - Cells and Molecular Products (Paperback, Softcover reprint of the original 1st ed. 1996)
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Invertebrate Immune Responses - Cells and Molecular Products (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: Advances in Comparative and Environmental Physiology, 23
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E. L. Cooper The Immunodefense System Because invertebrates are
exceedingly diverse and numerous, estimates reveal nearly 2 million
species classified in more than 20 phyla from unicellular organisms
up to the complex, multicellular protostomes and deuterostomes. It
is not surprising to find less diverse defense/immune responses
whose effector mechanisms remain to be completely elucidated. Of
course, I am not advocating that the few of us devoted to analyzing
invertebrate immunity attempt the Herculean task of examining all
these species to uncover some kind of unique response As these two
volumes will reveal, we are doing fairly well in examining in depth
only the most miniscule examples of invertebrates, some of which
have great effects on human populations such as edible crustaceans
or insect pests. This is in striking contrast to the mass of
information on the mammalian immune response which has been derived
essentially from the mouse, a member of one phylum, Vertebrata, an
approach, reductionist to be sure, but one that has served well
both the technological and conceptual advances of immunology as a
disci pline. The essential framework of immunology, the
overwhelming burst of results since the 1960s, have emanated
primarily from this single animal. We should not forget the thymus
and the bird's bursa of Fabricius, without which we might have been
slower to recognize the bipartite T /B system."
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