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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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The Epigenetics of Autoimmune Diseases (Hardcover, New)
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The Epigenetics of Autoimmune Diseases (Hardcover, New)
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The role of epigenetic mechanisms in autoimmune disease is only now
starting to become clear. Understanding these mechanisms, their
effect on cellular function and the role of environmental factors
is vital to determining how to manage these often debilitating and
fatal diseases. Drawing on the research of leading experts, this
book provides a valuable insight into this important new area of
autoimmunity research and a clear, up-to-date view on the major
advances in the field. Specific coverage includes: How highly
developed epigenetic mechanisms are involved in several aspects of
normal immune regulation, in addition to maintaining immune
tolerance to self-determinants. Specific epigenetic aspects of
human autoimmune diseases, including multiple sclerosis, systemic
lupus erythematosus, rheumatoid arthritis, systemic sclerosis,
autoimmune diabetes, thyroid autoimmunity, inflammatory bowel
disease and autoimmune hepatitis. How understanding epigenetic
mechanisms can lead to therapeutic strategies based on manipulation
of this previously unexploited facet of immune regulation.
Discussion of the novel approaches that are being investigated to
prevent or treat autoimmune diseases. This book is an essential
resource for those actively involved in the field. It is also of
interest to basic researchers interested in understanding the
origin of autoimmunity and clinical specialists interested in
gaining in-depth understanding of the pathogenesis of autoimmune
diseases and their treatment.
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