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More Dead Ends and Detours En Route to Successful Total Synthesis (Paperback)
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More Dead Ends and Detours En Route to Successful Total Synthesis (Paperback)
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Total price: R1,771
Discovery Miles: 17 710
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Success comes in many forms and in synthesis it can be a failure
that results in their ultimate successful solutions. This
long-awaited sequel to "Dead Ends and Detours" retains the proven
concept while featuring over 20 new case studies of failed
strategies and their (successful) solutions in natural product
total synthesis. Additionally, computational models are used to
discuss the problem in much more detail and to provide readers with
additional information not found in the primary literature. The
topics range from classic synthetic reactions (e.g. Diels Alder
reaction), metal-mediated coupling reactions, metathesis, and
asymmetric catalysis to the importance of protecting and activating
groups.
This book will benefit not only graduate students in organic
chemistry but also advanced researchers as they gain knowledge
derived from the step-by-step analysis of mistakes made in the past
and, thus be able to improve their own chemical reaction planning.
With its coverage of the most commonly applied reaction types, the
book perfectly complements its predecessor, which focuses on
general aspects, such as reactivity and selectivity.
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