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Pharmacotherapy of Pulmonary Hypertension (Paperback, Softcover reprint of the original 1st ed. 2013) Loot Price: R11,188
Discovery Miles 111 880
Pharmacotherapy of Pulmonary Hypertension (Paperback, Softcover reprint of the original 1st ed. 2013): Marc Humbert, Oleg V....

Pharmacotherapy of Pulmonary Hypertension (Paperback, Softcover reprint of the original 1st ed. 2013)

Marc Humbert, Oleg V. Evgenov, Johannes-Peter Stasch

Series: Handbook of Experimental Pharmacology, 218

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Loot Price R11,188 Discovery Miles 111 880 | Repayment Terms: R1,048 pm x 12*

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This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Handbook of Experimental Pharmacology, 218
Release date: August 2016
First published: 2013
Editors: Marc Humbert • Oleg V. Evgenov • Johannes-Peter Stasch
Dimensions: 235 x 155 x 30mm (L x W x T)
Format: Paperback
Pages: 576
Edition: Softcover reprint of the original 1st ed. 2013
ISBN-13: 978-3-662-52157-1
Categories: Books > Medicine > Clinical & internal medicine > Respiratory medicine
Books > Medicine > General issues > Medical equipment & techniques > Medical laboratory testing & techniques
Books > Medicine > General issues > Medical equipment & techniques > Medical research
Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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LSN: 3-662-52157-1
Barcode: 9783662521571

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