This book describes current methods for the identification and
characterization of the major hallmarks of senescent cells.
Chapters focus on the high heterogeneity of the senescence
phenotypes, and techniques to induce and identify specific
senescence programs. Additional chapters describe cellular and
mouse models in which is possible to study the complex cell and
non-cell autonomous functions of senescent cells. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Authoritative and cutting-edge, Cellular
Senescence: Methods and Protocols aims to ensure successful results
in the further study of this vital field.
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