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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Neuroprotective Signal Transduction (Paperback, 1998 ed.)
Loot Price: R4,273
Discovery Miles 42 730
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Neuroprotective Signal Transduction (Paperback, 1998 ed.)
Series: Contemporary Neuroscience
Expected to ship within 10 - 15 working days
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In Neuroprotective Signal Transduction prominent researchers and
clinicians focus on how inter- and intracellular signaling
mechanisms prevent the degeneration and death of neurons occurring
in both acute and chronic neurodegenerative disorders.
Authoritative contributions dissect the signaling pathways of an
array of neuroprotective factors-ranging from neurotrophins (NGF,
BDNF, NT-3, and NT-4/5), to growth factors (bFGF, IGF-1, GDNF), to
cytokines (TNF, IL-1b, and TGFb), to secreted amyloid precursor
proteins, to protease nexin-1. Also treated are cytoprotective
signaling events that occur within injured neurons independently of
intercellular signals. Neuroprotective Signal Transduction presents
fundamental, cutting-edge treatment of the cellular and molecular
signal transduction pathways found in human neurodegenerative
conditions. The book's elucidation of the molecular cascades
evolved by the nervous system to protect itself is now lead to
effective strategies for preventing neuronal degeneration in such
conditions as stroke, traumatic brain injury, Alzheimer's disease,
Parkinson's disease, Huntington's disease, and amyotrophic lateral
sclerosis, and will form the basis for powerful new drug discovery
and gene therapy strategies.
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