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Books > Medicine > Other branches of medicine > Medical imaging
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Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) (Hardcover, 2nd Revised edition)
Loot Price: R5,364
Discovery Miles 53 640
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Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) (Hardcover, 2nd Revised edition)
Expected to ship within 18 - 22 working days
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The area of molecular imaging has matured over the past decade and
is still growing rapidly. Many concepts developed for molecular
biology and cellular imaging have been successfully translated to
in vivo imaging of intact organisms. Molecular imaging enables the
study of processes at a molecular level in their full biological
context. Due to the high specificity of the molecular readouts the
approach bears a high potential for diagnostics. It is fair to say
that molecular imaging has become an indispensable tool for
biomedical research and drug discovery and development today.This
volume familiarizes the reader with the concepts of imaging and
molecular imaging in particular. Basic principles of imaging
technologies, reporter moieties for the various imaging modalities,
and the design of targeted probes are described in the first part.
The second part illustrates how these tools can be used to
visualize relevant molecular events in the living organism. Topics
covered include the studies of the biodistribution of reporter
probes and drugs, visualization of the expression of biomolecules
such as receptors and enzymes, and how imaging can be used for
analyzing consequences of the interaction of a ligand or a drug
with its molecular target by visualizing signal transduction, or
assessing the metabolic, physiological, or structural response of
the organism studied. The final chapter deals with visualization of
cell migration, for example in the context of cell therapies.The
second edition covers novel developments over recent years, in
particular regarding imaging technologies (hybrid techniques) and
novel reporter concepts. Novel biomedical applications have been
included, where appropriate. All the chapters have been thoroughly
reworked and the artwork updated.
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