In Neurology of Autism, Mary Coleman, Catalina Betancur, G. Robert
DeLong, Christopher Gillberg, Yoshiko Nomura, Lorenzo Pavone,
Martin Ruggieri, and Michele Zappella use the tools of neurological
analysis to address a number of the major questions that have
arisen in the study of autism. The answers they present have
important implications for the direction of future autism research,
diagnosis, and treatment.
What are the neurological signs and symptoms of autism? The latest
information is presented here in an in-depth discussion of
epilepsy, cranial circumference, changes in muscle tone,
stereotypies, and mutism found in children with autism. In
addition, a template is provided for practitioners to follow when
conducting neurological examinations of a child with autism. What
are the best options for the treatment of autism? The current
medical, educational, and alternative therapies are thoroughly
reviewed and evaluated. Is autism reversible? The question is
explored for syndromic autism, where diseases may have a transient
autistic phase, and reviewed in detail for nonsyndromic
autism.
Is autism primarily a single disease, as originally described by
Leo Kanner? Research presented here suggests that autism is,
instead, a syndrome involving many disease entities. Has the
incidence of autism been increasing in recent years? A
sophisticated, historical review of autisms prevalence rates
suggests that it has never been rare. What is the relationship
between autism and Asperger syndrome? The latest evidence presented
here sheds light on the degree to which both syndromes share more
than clinical characteristics; they also have some similar findings
in imaging, neuropathological, and genetic studies. Which
components of the brains neural networks need to be impaired to
cause the appearance of autistic symptoms? Although there are many
candidate regions, dysfunction of the cerebellum and its circuits
is noted to be of great interest. Student and professional
researchers, practitioners, and parents will find this book to be a
valuable resource for both the latest information from
basic-science research and its application to the diagnosis and
treatment of autism.
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