Regucalcin is a protein which is highly differentiated due to
increased conservation of the regucalcin genes throughout evolution
in vertebrates. Regucalcin plays a multifunctional role in cellular
regulation, including an inhibitory role in protein kinases,
protein phosphatases, NO synthase, nuclear DNA and RNA synthesis.
Regucalcin suppresses an enhancement of cell proliferation and
apoptotic cell death that are induced by various signalling
factors. Regucalcin plays a pathophysiological role in many
metabolic disorders in humans. This book introduces recent topics
of regucalcin studies concerning the genomics, cell regulation and
diseases associated with this protein.
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