This issue of Interventional Cardiology Clinics, guest edited by
Editor-in-Chief Matthew J. Price, will focus on Key Trials of the
Decade. Trials discussed in this issue will include: Physiology
over Angiography to determine lesion severity: The FAME trials;
Percutaneous Coronary Intervention or surgery for multivessel
disease: The SYNTAX trial at 10 years; Percutaneous Coronary
Intervention or surgery for unprotected left main disease: The
EXCEL trial at 5 years; Complete or Incomplete Revascularization
for ST-Elevation Myocardial Infarction: the PRAMI trial and beyond;
Abbreviated Dual Antiplatelet Therapy after PCI in High Bleeding
Risk Patients: LEADERS-FREE and ONYX ONE; Transcatheter treatment
of functional mitral regurgitation in patients with heart failure:
The COAPT trial; Manual thrombectomy in Primary Percutaneous
Coronary Intervention: Lessons learned from TOTAL; Paradigm shifts
in the treatment of aortic stenosis: The PARTNER Trials experience;
COURAGE and ORBITA in context: PCI for chronic stable CAD;
SIMPLICITY to RADIANCE: Interpreting the past and mapping the
future of renal denervation; From WOEST to AUGUSTUS: Dual Therapy
after PCI; The ISCHEMIA Trial: Background, Design, Outcomes and
Clinical Interpretation.
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