Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Vitiligo (Hardcover, 2010 ed.)
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Vitiligo (Hardcover, 2010 ed.)
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Vitiligo has been, until recently, a rather neglected area in
dermatology and medicine. Patients complain about this situation,
which has offered avenues to quacks, and has led to the near orphan
status of the disease. The apparently, simple and poorly
symptomatic presentation of the disease has been a strong
disadvantage to its study, as compared to other common chronic skin
disorders such as psoriasis and atopic dermatitis. Vitiligo is
still considered by doctors as a non disease, a simple aesthetic
problem. A good skin-based angle of attack is also lacking because
generalized vi- ligo is clearly epitomizing the view of skin
diseases as simple targets of a systemic unknown dysregulation
(diathesis), re? ecting the Hippocratic doctrine. This view has
mostly restricted vitiligo to the manifestation of an auto-immune
diathesis in the past 30 years. Thus, skin events, which are easily
detected using skin biospies in most other situations, have not
been precisely recorded, with the argument that a clinical
diagnosis was suf? cient for the management (or most commonly
absence of mana- ment) of the patient. This book is an
international effort to summarize the information gathered about
this disorder at the clinical, pathophysiological and therapeutic
levels. Its primary aim is to bridge current knowledge at the
clinical and investigative level, to point to the many unsolved
issues, and to delineate future priorities for research.
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